The Cell Death Pathway Regulates Synapse Elimination through Cleavage of Gelsolin in Caenorhabditis elegans Neurons

Synapse elimination occurs in development, plasticity, and disease. Although the importance of synapse elimination has been documented in many studies, the molecular mechanisms underlying this process are unclear. Here, using the development of C. elegans RME neurons as a model, we have uncovered a...

Full description

Bibliographic Details
Main Authors: Lingfeng Meng, Ben Mulcahy, Steven J. Cook, Marianna Neubauer, Airong Wan, Yishi Jin, Dong Yan
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715005677