Cloning and expression of recombinant purine nucleoside phosphorylase in the methylotrophic yeast Pichia pastoris

Cloning and expression of recombinant purine nucleoside phosphorylase in the methylotrophic yeast Pichia pastoris

Purine Nucleoside Phosphorylase (PNP) is an enzyme involved in biosynthetic pathway of purine nucleosides. Purine nucleoside phosphorylase catalyzes the cleavage of the glycosidic bond of ribo- or deoxyribonucleosides to form the purine base and deoxyribose- or ribose-1-phosphate. The reversible rea...

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Bibliographic Details
Main Authors: Jaloliddin Abdurakhmanov, Sobirdjan Sasmakov, Shukhrat Khasanov, Oybek Ashirov, Farkhod Eshboev, Khayotjon Dolimov, Saodat Gaynazarova, Tulkin Sadullaev, Oygul Yarilkaganova, Khusan Nasriddinov, Asadali Baymirzaev, Artyom Makhnyov, Shakhnoz Azimova
Format: Article
Language:English
Published: Bangladesh Society for Microbiology, Immunology, and Advanced Biotechnology 2023-12-01
Series:Journal of Advanced Biotechnology and Experimental Therapeutics
Subjects:
inosine
enzymatic hydrolysis
modified nucleosides
pichia pastoris
purine nucleoside phosphorylase
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=149208

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