Evaluation of the Role of p53 Tumour Suppressor Posttranslational Modifications and TTC5 Cofactor in Lung Cancer

Evaluation of the Role of p53 Tumour Suppressor Posttranslational Modifications and TTC5 Cofactor in Lung Cancer

Mutations in the p53 tumor suppressor are found in over 50% of cancers. p53 function is controlled through posttranslational modifications and cofactor interactions. In this study, we investigated the posttranslationally modified p53, including p53 acetylated at lysine 382 (K382), p53 phosphorylated...

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Bibliographic Details
Main Authors: Hasen Alhebshi, Kun Tian, Lipsita Patnaik, Rebecca Taylor, Pavel Bezecny, Callum Hall, Patricia Anthonia Johanna Muller, Nazila Safari, Delta Patricia Menendez Creamer, Constantinos Demonacos, Luciano Mutti, Mohamad Nidal Bittar, Marija Krstic-Demonacos
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
p53
TTC5
lung cancer
Online Access:https://www.mdpi.com/1422-0067/22/24/13198

Internet

https://www.mdpi.com/1422-0067/22/24/13198

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