Inhibition of type I PRMTs reforms muscle stem cell identity enhancing their therapeutic capacity

In skeletal muscle, muscle stem cells (MuSC) are the main cells responsible for regeneration upon injury. In diseased skeletal muscle, it would be therapeutically advantageous to replace defective MuSCs, or rejuvenate them with drugs to enhance their self-renewal and ensure long-term regenerative po...

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Bibliographic Details
Main Authors: Claudia Dominici, Oscar D Villarreal, Junio Dort, Emilie Heckel, Yu Chang Wang, Ioannis Ragoussis, Jean-Sebastien Joyal, Nicolas Dumont, Stéphane Richard
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/84570