Intraplatelet Calcium Signaling Regulates Thrombus Growth under Flow: Insights from a Multiscale Model

In injured arteries, platelets adhere to the subendothelium and initiate the coagulation process. They recruit other platelets and form a plug that stops blood leakage. The formation of the platelet plug depends on platelet activation, a process that is regulated by intracellular calcium signaling....

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Bibliographic Details
Main Authors: Anass Bouchnita, Vitaly Volpert
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Series:Computation
Subjects:
Online Access:https://www.mdpi.com/2079-3197/12/5/99