Long-Term Optical Access to an Estimated One Million Neurons in the Live Mouse Cortex

Long-Term Optical Access to an Estimated One Million Neurons in the Live Mouse Cortex

A major technological goal in neuroscience is to enable the interrogation of individual cells across the live brain. By creating a curved glass replacement to the dorsal cranium and surgical methods for its installation, we developed a chronic mouse preparation providing optical access to an estimat...

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Bibliographic Details
Main Authors: Tony Hyun Kim, Yanping Zhang, Jérôme Lecoq, Juergen C. Jung, Jane Li, Hongkui Zeng, Cristopher M. Niell, Mark J. Schnitzer
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Cell Reports
Subjects:
neocortex
calcium imaging
brain imaging
mouse behavior
dendrites
dendritic spines
neural ensembles
two-photon microscopy
fluorescence imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471631676X

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http://www.sciencedirect.com/science/article/pii/S221112471631676X

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