Combined enhancement of the propionyl-CoA metabolic pathway for efficient androstenedione production in Mycolicibacterium neoaurum

Combined enhancement of the propionyl-CoA metabolic pathway for efficient androstenedione production in Mycolicibacterium neoaurum

Abstract Background The production of androstenedione (AD) from phytosterols by Mycolicibacterium neoaurum is a multi-step biotransformation process, which requires degradation of sterol side chains, accompanied by the production of propionyl-CoA. However, the transient production of large amounts o...

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Bibliographic Details
Main Authors: Zhenhua Su, Zhenjian Zhang, Jian Yu, Congcong Yuan, Yanbing Shen, Jianxin Wang, Liqiu Su, Min Wang
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Microbial Cell Factories
Subjects:
Mycolicibacterium neoaurum
Androstenone
Propionyl-CoA metabolic
Pathway Associates
Online Access:https://doi.org/10.1186/s12934-022-01942-x

Internet

https://doi.org/10.1186/s12934-022-01942-x

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