Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery

It is well known that the pH of tumor tissue is lower than that of the corresponding normal adjacent tissue. Here, the authors report a clinical trial of a pH activatable nanoparticle for imaging tumours.

Bibliographic Details
Main Authors: F. J. Voskuil, P. J. Steinkamp, T. Zhao, B. van der Vegt, M. Koller, J. J. Doff, Y. Jayalakshmi, J. P. Hartung, J. Gao, B. D. Sumer, M. J. H. Witjes, G. M. van Dam, the SHINE study group
Format: Article
Language:English
Published: Nature Portfolio 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16814-4