Duloxetine hydrochloride loaded film forming dermal gel enriched with methylcobalamin and geranium oil attenuates paclitaxel-induced peripheral neuropathy in rats

Objective: In attempt to conquer the major concerns of oral duloxetine hydrochloride (like low bioavailability, intolerable side-effects and no regeneration of demyelinated nerve fibres) for the management of chemotherapy-induced peripheral neuropathy (CIPN), an alternative delivery of duloxetine hy...

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Bibliographic Details
Main Authors: Simerjeet Kaur Chahal, Rupinder Kaur Sodhi, Jitender Madan
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:IBRO Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451830120300297