Duloxetine hydrochloride loaded film forming dermal gel enriched with methylcobalamin and geranium oil attenuates paclitaxel-induced peripheral neuropathy in rats
Objective: In attempt to conquer the major concerns of oral duloxetine hydrochloride (like low bioavailability, intolerable side-effects and no regeneration of demyelinated nerve fibres) for the management of chemotherapy-induced peripheral neuropathy (CIPN), an alternative delivery of duloxetine hy...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-12-01
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Series: | IBRO Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2451830120300297 |