Protein abundance of AKT and ERK pathway components governs cell type‐specific regulation of proliferation

Protein abundance of AKT and ERK pathway components governs cell type‐specific regulation of proliferation

Abstract Signaling through the AKT and ERK pathways controls cell proliferation. However, the integrated regulation of this multistep process, involving signal processing, cell growth and cell cycle progression, is poorly understood. Here, we study different hematopoietic cell types, in which AKT an...

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Bibliographic Details
Main Authors: Lorenz Adlung, Sandip Kar, Marie‐Christine Wagner, Bin She, Sajib Chakraborty, Jie Bao, Susen Lattermann, Melanie Boerries, Hauke Busch, Patrick Wuchter, Anthony D Ho, Jens Timmer, Marcel Schilling, Thomas Höfer, Ursula Klingmüller
Format: Article
Language:English
Published: Springer Nature 2017-01-01
Series:Molecular Systems Biology
Subjects:
32D‐EpoR
BaF3‐EpoR
CFU‐E
MAPK
PI3K
Online Access:https://doi.org/10.15252/msb.20167258

Internet

https://doi.org/10.15252/msb.20167258

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