Heat shock protein 90 inhibition attenuates inflammation in models of atopic dermatitis: a novel mechanism of action
BackgroundHeat shock protein 90 (HSP90) is an important chaperone supporting the function of many proinflammatory client proteins. Recent studies indicate HSP90 inhibition may be a novel mechanism of action for inflammatory skin diseases; however, this has not been explored in atopic dermatitis (AD)...
Main Authors: | Hakim Ben Abdallah, Anne Bregnhøj, Gautam Ghatnekar, Lars Iversen, Claus Johansen |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2024-01-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1289788/full |
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