Oncofetal protein IGF2BPs in human cancer: functions, mechanisms and therapeutic potential

Abstract N6-methyladenosine (m6A) is the most prevalent and well-characterized internal chemical modification in eukaryotic RNA, influencing gene expression and phenotypic changes by controlling RNA fate. Insulin-like growth factor-2 mRNA-binding proteins (IGF2BPs) preferentially function as m6A eff...

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Bibliographic Details
Main Authors: Tian-Yu Zhu, Lian-Lian Hong, Zhi-Qiang Ling
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Biomarker Research
Subjects:
Online Access:https://doi.org/10.1186/s40364-023-00499-0