Cinnamomum verum component 2-methoxycinnamaldehyde: a novel antiproliferative drug inducing cell death through targeting both topoisomerase I and II in human colorectal adenocarcinoma COLO 205 cells

Background: Cinnamomum verum is used to manufacture the spice cinnamon. In addition, the plant has been used as a Chinese herbal medication. Methods: We investigated the antiproliferative effect of 2-methoxycinnamaldehyde (2-MCA), a constituent of the cortex of the plant, and the molecular biomarker...

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Bibliographic Details
Main Authors: Kuen-daw Tsai, Jonathan Cherng, Yi-Heng Liu, Ta-Wei Chen, Ho-Yiu Wong, Shu-mei Yang, Kuo-Shen Chou, Jaw-Ming Cherng
Format: Article
Language:English
Published: Swedish Nutrition Foundation 2016-06-01
Series:Food & Nutrition Research
Subjects:
Online Access:http://www.foodandnutritionresearch.net/index.php/fnr/article/view/31607/46969