Downregulation of PDIA3 inhibits gastric cancer cell growth through cell cycle regulation

Downregulation of PDIA3 inhibits gastric cancer cell growth through cell cycle regulation

Objective: Protein disulfide isomerase A3 (PDIA3) promotes the correct folding of newly synthesized glycoproteins in the endoplasmic reticulum. PDIA3 is overexpressed in most tumors, and it may become a biomarker of cancer prognosis and immunotherapy. Our study aims to detect the expression level of...

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Bibliographic Details
Main Authors: Min Yang, Qianxiu Li, Huan Yang, Yifan Li, Lan Lu, Xu Wu, Yubin Liu, Wanping Li, Jing Shen, Zhangang Xiao, Yueshui Zhao, Fukuan Du, Yu Chen, Shuai Deng, Chi Hin Cho, Xiaobing Li, Mingxing Li
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
PDIA3
Gastric cancer
CCNG1
CRISPR-Cas9
STAT3
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224002208

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http://www.sciencedirect.com/science/article/pii/S0753332224002208

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