Polydiacetylene-based high-throughput screen for surfactin producing strains of Bacillus subtilis.

Although traditional mutation is still an attractive approach for strain improvement, it is tedious, time-consuming, and inefficient to screen for surfactin producing strains. To overcome this, we developed a high-throughput screening method for surfactin producing mutants by applying polydiacetylen...

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Bibliographic Details
Main Authors: Lingyan Zhu, Qing Xu, Ling Jiang, He Huang, Shuang Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3912180?pdf=render