CSF1R antagonism results in increased supraspinal infiltration in EAE
Abstract Background Colony stimulating factor 1 receptor (CSF1R) signaling is crucial for the maintenance and function of various myeloid subsets. CSF1R antagonism was previously shown to mitigate clinical severity in experimental autoimmune encephalomyelitis (EAE). The associated mechanisms are sti...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-04-01
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Series: | Journal of Neuroinflammation |
Online Access: | https://doi.org/10.1186/s12974-024-03063-1 |