CSF1R antagonism results in increased supraspinal infiltration in EAE

Abstract Background Colony stimulating factor 1 receptor (CSF1R) signaling is crucial for the maintenance and function of various myeloid subsets. CSF1R antagonism was previously shown to mitigate clinical severity in experimental autoimmune encephalomyelitis (EAE). The associated mechanisms are sti...

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Bibliographic Details
Main Authors: Marilyn Wang, Sofia E. Caryotakis, Glendalyn G. Smith, Alan V. Nguyen, David E. Pleasure, Athena M. Soulika
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Neuroinflammation
Online Access:https://doi.org/10.1186/s12974-024-03063-1