SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome

<p>Abstract</p> <p>Specific peptide ligand recognition by modular interaction domains is essential for the fidelity of information flow through the signal transduction networks that control cell behavior in response to extrinsic and intrinsic stimuli. Src homology 2 (SH2) domains r...

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Bibliographic Details
Main Authors: Liu Bernard A, Engelmann Brett W, Jablonowski Karl, Higginbotham Katherine, Stergachis Andrew B, Nash Piers D
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Cell Communication and Signaling
Online Access:http://www.biosignaling.com/content/10/1/27