Signaling pathways and posttranslational modifications of tau in Alzheimer’s disease: the humanization of yeast cells

In the past decade, yeast have been frequently employed to study the molecular mechanisms of human neurodegenerative diseases, generally by means of heterologous expression of genes encoding the relevant hallmark proteins. However, it has become evident that substantial posttranslational modificatio...

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Bibliographic Details
Main Authors: Jürgen J. Heinisch, Roland Brandt
Format: Article
Language:English
Published: Shared Science Publishers OG 2016-03-01
Series:Microbial Cell
Subjects:
Online Access:http://microbialcell.com/researcharticles/signaling-pathways-and-posttranslational-modifications-of-tau-in-alzheimers-disease-the-humanization-of-yeast-cells/