The Non-Specific Drp1 Inhibitor Mdivi-1 Has Modest Biochemical Antioxidant Activity

The Non-Specific Drp1 Inhibitor Mdivi-1 Has Modest Biochemical Antioxidant Activity

Mitochondrial division inhibitor-1 (mdivi-1), a non-specific inhibitor of Drp1-dependent mitochondrial fission, is neuroprotective in numerous preclinical disease models. These include rodent models of Alzheimer’s disease and ischemic or traumatic brain injury. Among its Drp1-independent actions, th...

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Bibliographic Details
Main Authors: Evan A. Bordt, Naibo Zhang, Jaylyn Waddell, Brian M. Polster
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Antioxidants
Subjects:
ROS
oxidative stress
free radical
scavenger
superoxide
oxygen
Online Access:https://www.mdpi.com/2076-3921/11/3/450

Internet

https://www.mdpi.com/2076-3921/11/3/450

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