ELISpots Assay to Measure the Number of Murine Plasma Cells Producing Anti-dsDNA Antibodies

Circulating anti-dsDNA antibody is a hallmark of SLE both in human patients and in many SLE mouse models. This protocol describes how to measure the frequency of plasma cells producing these antibodies in the spleen of lupus-prone mice. This protocol was developed or modified in Dr. Anne Davidson’s...

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Bibliographic Details
Main Author: Zheng Liu
Format: Article
Language:English
Published: Bio-protocol LLC 2011-12-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=34&type=0