Modulation of the vitamin D/vitamin D receptor system in osteoporosis pathogenesis: insights and therapeutic approaches

Modulation of the vitamin D/vitamin D receptor system in osteoporosis pathogenesis: insights and therapeutic approaches

Abstract Osteoporosis is a prevalent bone disorder characterized by low bone mineral density (BMD) and deteriorated bone microarchitecture, leading to an increased risk of fractures. Vitamin D (VD), an essential nutrient for skeletal health, plays a vital role in maintaining bone homeostasis. The bi...

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Bibliographic Details
Main Authors: Yanqi Li, Pengfei Zhao, Biyun Jiang, Kangyong Liu, Lei Zhang, Haotian Wang, Yansheng Tian, Kun Li, Guoqi Liu
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteoporosis
Vitamin D receptor
Bone mineral density
Bone remodeling
Calcium metabolism
Genetic variations
Online Access:https://doi.org/10.1186/s13018-023-04320-4

Internet

https://doi.org/10.1186/s13018-023-04320-4

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