DlgS97/SAP97, a neuronal isoform of discs large, regulates ethanol tolerance.

DlgS97/SAP97, a neuronal isoform of discs large, regulates ethanol tolerance.

From a genetic screen for Drosophila melanogaster mutants with altered ethanol tolerance, we identified intolerant (intol), a novel allele of discs large 1 (dlg1). Dlg1 encodes Discs Large 1, a MAGUK (Membrane Associated Guanylate Kinase) family member that is the highly conserved homolog of mammali...

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Bibliographic Details
Main Authors: Rajani Maiya, Seonok Lee, Karen H Berger, Eric C Kong, Justin B Slawson, Leslie C Griffith, Kogo Takamiya, Richard L Huganir, Ben Margolis, Ulrike Heberlein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492131?pdf=render

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http://europepmc.org/articles/PMC3492131?pdf=render

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