Analysis of the Bile Salt Export Pump (ABCB11) Interactome Employing Complementary Approaches.

The bile salt export pump (BSEP, ABCB11) plays an essential role in the formation of bile. In hepatocytes, BSEP is localized within the apical (canalicular) membrane and a deficiency of canalicular BSEP function is associated with severe forms of cholestasis. Regulation of correct trafficking to the...

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Bibliographic Details
Main Authors: Susanne Przybylla, Jan Stindt, Diana Kleinschrodt, Jan Schulte Am Esch, Dieter Häussinger, Verena Keitel, Sander H Smits, Lutz Schmitt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4966956?pdf=render