Gas2l3, a novel constriction site-associated protein whose regulation is mediated by the APC/C Cdh1 complex.

Growth arrest-specific 2-like protein 3 (Gas2l3) was recently identified as an Actin/Tubulin cross-linker protein that regulates cytokinesis. Using cell-free systems from both frog eggs and human cells, we show that the Gas2l3 protein is targeted for ubiquitin-mediated proteolysis by the APC/C(Cdh1)...

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Bibliographic Details
Main Authors: Tal Pe'er, Roxane Lahmi, Yaara Sharaby, Evelin Chorni, Meirav Noach, Manuela Vecsler, Eitan Zlotorynski, Hanno Steen, Judith A Steen, Amit Tzur
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585356?pdf=render