How Lipid-Specific T Cells Become Effectors: The Differentiation of iNKT Subsets

In contrast to peptide-recognizing T cells, invariant natural killer T (iNKT) cells express a semi-invariant T cell receptor that specifically recognizes self- or foreign-lipids presented by CD1d molecules. There are three major functionally distinct effector states for iNKT cells. Owning to these i...

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Bibliografske podrobnosti
Main Authors: Haiguang Wang, Kristin A. Hogquist
Format: Article
Jezik:English
Izdano: Frontiers Media S.A. 2018-06-01
Serija:Frontiers in Immunology
Teme:
Online dostop:https://www.frontiersin.org/article/10.3389/fimmu.2018.01450/full