Quantitative Determination and Toxicity Evaluation of Aristolochic Acid Analogues in Asarum heterotropoides F. Schmidt (Xixin) and Traditional Chinese Patent Medicines

Asarum (Xixin), which contains analogues of aristolochic acid (AA), is the only species of the genus Aristolochia included in the Chinese Pharmacopoeia 2020. However, the contents and nephrotoxic effects of AA analogs in Asarum (Xixin) and its formulations have not been clarified. An automatic, effe...

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Bibliographic Details
Main Authors: Suyan Liu, Zhong Xian, Yong Zhao, Lianmei Wang, Jingzhuo Tian, Chen Pan, Jiayin Han, Yushi Zhang, Chunying Li, Yan Yi, Chenyue Liu, Dunfang Wang, Jing Meng, Shasha Qin, Fang Wang, Aihua Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.761593/full