Effect of DIO2 Gene Polymorphism on Thyroid Hormone Levels and Its Correlation with the Severity of Schizophrenia in a Pakistani Population

Effect of DIO2 Gene Polymorphism on Thyroid Hormone Levels and Its Correlation with the Severity of Schizophrenia in a Pakistani Population

Low levels of triiodothyronine (T3) in the brain lead to increased dopamine receptor sensitivity, potentially resulting in schizophrenia. Iodothyronine deiodinase 2 (DIO2) is the only enzyme which converts tetraiodothyronine (T4) to T3 in the brain. <i>DIO2</i> polymorphism of rs225014 r...

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Bibliographic Details
Main Authors: Farina Hanif, Quratulain Amir, Washdev Washdev
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
tetraiodothyronine (T4)
triiodothyronine (T3)
PANSS
genotyping
iodothyronine deiodinase 2
rs225014
Online Access:https://www.mdpi.com/1422-0067/25/3/1915

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https://www.mdpi.com/1422-0067/25/3/1915

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