Economic and Practical Factors in Diagnosing HNPCC Using Clinical Criteria, Immunohistochemistry and Microsatellite Instability Analysis

Economic and Practical Factors in Diagnosing HNPCC Using Clinical Criteria, Immunohistochemistry and Microsatellite Instability Analysis

<p>Abstract</p> <p>Aim</p> <p>To determine a cost-efficient strategy for HNPCC molecular diagnostic testing.</p> <p>Methods</p> <p>138 families referred to a Regional Genetics Service had hMLH1 and hMSH2 mutation analysis. The sensitivity and spe...

Full description

Bibliographic Details
Main Authors: Pigatto Francesca, Bateman Adrian, Bunyan David, Strike Paul, Wilkins Esta, Curtis Claire, Duncan Philippa, May Denzil, Nugent Karen, Eccles Diana
Format: Article
Language:English
Published: BMC 2004-11-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
HNPCC
mutation analysis
clinical criteria
immunohistochemistry
microsatellite instability
cost analysis
Online Access:http://www.hccpjournal.com/content/2/4/175

Internet

http://www.hccpjournal.com/content/2/4/175

Similar Items