pH- and sodium-induced changes in a sodium/proton antiporter

We examined substrate-induced conformational changes in MjNhaP1, an archaeal electroneutral Na+/H+-antiporter resembling the human antiporter NHE1, by electron crystallography of 2D crystals in a range of physiological pH and Na+ conditions. In the absence of sodium, changes in pH had no major effec...

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Bibliographic Details
Main Authors: Cristina Paulino, Werner Kühlbrandt
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/01412