Identification of potential therapeutic targets for COVID-19 through a structural-based similarity approach between SARS-CoV-2 and its human host proteins

Identification of potential therapeutic targets for COVID-19 through a structural-based similarity approach between SARS-CoV-2 and its human host proteins

Background: The COVID-19 pandemic caused by SARS-CoV-2 has led to millions of deaths worldwide, and vaccination efficacy has been decreasing with each lineage, necessitating the need for alternative antiviral therapies. Predicting host–virus protein–protein interactions (HV-PPIs) is essential for id...

Full description

Bibliographic Details
Main Authors: Alvea Tasneem, Armiya Sultan, Prithvi Singh, Hridoy R. Bairagya, Hassan Hussain Almasoudi, Abdulfattah Yahya M. Alhazmi, Abdulkarim S. Binshaya, Mohammed Ageeli Hakami, Bader S. Alotaibi, Alaa Abdulaziz Eisa, Abdulaziz Saleh I. Alolaiqy, Mohammad Raghibul Hasan, Kapil Dev, Ravins Dohare
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Genetics
Subjects:
COVID-19
virus–host target proteins
structural-based similarity
PPI network
SARS-CoV-2
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1292280/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2024.1292280/full

Similar Items