Clinico-Pathological Importance of TGF-β/Phospho-Smad Signaling during Human Hepatic Fibrocarcinogenesis

Clinico-Pathological Importance of TGF-β/Phospho-Smad Signaling during Human Hepatic Fibrocarcinogenesis

Chronic viral hepatitis is a global public health problem, with approximately 570 million persons chronically infected. Hepatitis B and C viruses increase the risk of morbidity and mortality from liver cirrhosis, hepatocellular carcinoma (HCC), and extrahepatic complications that develop. Hepatitis...

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Bibliographic Details
Main Authors: Katsunori Yoshida, Koichi Matsuzaki, Miki Murata, Takashi Yamaguchi, Kanehiko Suwa, Kazuichi Okazaki
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Cancers
Subjects:
transforming growth factor (TGF)-β
Smad
hepatic stellate cells (HSC)
myofibroblasts (MFB)
liver fibrocarcinogenesis
Online Access:http://www.mdpi.com/2072-6694/10/6/183

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http://www.mdpi.com/2072-6694/10/6/183

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