A computational model of stem cells’ decision-making mechanism to maintain tissue homeostasis and organization in the presence of stochasticity
Abstract The maintenance of multi-cellular developed tissue depends on the proper cell production rate to replace the cells destroyed by the programmed process of cell death. The stem cell is the main source of producing cells in a developed normal tissue. It makes the stem cell the lead role in the...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-12717-0 |