Simvastatin prevents dopaminergic neurodegeneration in experimental parkinsonian models: the association with anti-inflammatory responses.

Simvastatin prevents dopaminergic neurodegeneration in experimental parkinsonian models: the association with anti-inflammatory responses.

<h4>Background</h4>In addition to their original applications to lowering cholesterol, statins display multiple neuroprotective effects. N-methyl-D-aspartate (NMDA) receptors interact closely with the dopaminergic system and are strongly implicated in therapeutic paradigms of Parkinson&#...

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Main Authors: Junqiang Yan, Yunqi Xu, Cansheng Zhu, Limin Zhang, Aimin Wu, Yu Yang, Zhaojun Xiong, Chao Deng, Xu-Feng Huang, Midori A Yenari, Yuan-Guo Yang, Weihai Ying, Qing Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21731633/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21731633/?tool=EBI

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