Disambiguate: An open-source application for disambiguating two species in next generation sequencing data from grafted samples [version 2; referees: 3 approved]

Grafting of cell lines and primary tumours is a crucial step in the drug development process between cell line studies and clinical trials. Disambiguate is a program for computationally separating the sequencing reads of two species derived from grafted samples. Disambiguate operates on DNA or RNA-s...

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Bibliographic Details
Main Authors: Miika J. Ahdesmäki, Simon R. Gray, Justin H. Johnson, Zhongwu Lai
Format: Article
Language:English
Published: F1000 Research Ltd 2017-01-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/5-2741/v2