Substrates incorporating unnatural amino acids are separately detectable for chymotrypsin and subtilisin with similar specificity
Protease specificity depends on the three-dimensional structure and sequence of the protease, and each protease plays a different role. Chymotrypsin and subtilisin have similar specificity for recognizing aromatic and hydrophobic amino acid residues. Previous methods using natural amino acids have d...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | Results in Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715623004563 |