A survey of the specificity and mechanism of 1,6 hexanediol-induced disruption of nuclear transport

A survey of the specificity and mechanism of 1,6 hexanediol-induced disruption of nuclear transport

ABSTRACTSelective transport through the nuclear pore complex (NPC) depends on the dynamic binding of FG-repeat containing nucleoporins, the FG-nups, with each other and with Karyopherins (Kaps). Here, we assessed the specificity and mechanism by which the aliphatic alcohol 1,6-hexanediol (1,6HD) dis...

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Bibliographic Details
Main Authors: Elizabeth C. Riquelme Barrientos, Tegan A. Otto, Sara N. Mouton, Anton Steen, Liesbeth M. Veenhoff
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Nucleus
Subjects:
1,6-hexanediol
aliphatic alcohol
baker’s yeast
Karyopherin
liquid-liquid phase separation
Nuclear pore complex
Online Access:https://www.tandfonline.com/doi/10.1080/19491034.2023.2240139

Internet

https://www.tandfonline.com/doi/10.1080/19491034.2023.2240139

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