Dissecting phenotypic transitions in metastatic disease via photoconversion-based isolation

Cancer patients often harbor occult metastases, a potential source of relapse that is targetable only through systemic therapy. Studies of this occult fraction have been limited by a lack of tools with which to isolate discrete cells on spatial grounds. We developed PIC-IT, a photoconversion-based i...

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Bibliographic Details
Main Authors: Yogev Sela, Jinyang Li, Paola Kuri, Allyson J Merrell, Ning Li, Chris Lengner, Pantelis Rompolas, Ben Z Stanger
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/63270