The Effect of a New Glucose–Methotrexate Conjugate on Acute Lymphoblastic Leukemia and Non-Hodgkin’s Lymphoma Cell Lines

Patients with hematologic malignancies require intensive therapies, including high-dose chemotherapy. Antimetabolite–methotrexate (MTX) has been used for many years in the treatment of leukemia and in lymphoma patients. However, the lack of MTX specificity causes a significant risk of morbidity, mor...

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Bibliographic Details
Main Authors: Marta Woźniak, Sebastian Makuch, Gabriela Pastuch-Gawołek, Jerzy Wiśniewski, Wiesław Szeja, Martyna Nowak, Monika Krawczyk, Siddarth Agrawal
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/9/2547