Exposure to Stress Alters Cardiac Gene Expression and Exacerbates Myocardial Ischemic Injury in the Female Murine Heart

Exposure to Stress Alters Cardiac Gene Expression and Exacerbates Myocardial Ischemic Injury in the Female Murine Heart

Mental stress is a risk factor for myocardial infarction in women. The central hypothesis of this study is that restraint stress induces sex-specific changes in gene expression in the heart, which leads to an intensified response to ischemia/reperfusion injury due to the development of a pro-oxidati...

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Bibliographic Details
Main Authors: Hemangini A. Dhaibar, Lilly Kamberov, Natalie G. Carroll, Shripa Amatya, Dario Cosic, Oscar Gomez-Torres, Shantel Vital, Farzane Sivandzade, Aditya Bhalerao, Salvatore Mancuso, Xinggui Shen, Hyung Nam, A. Wayne Orr, Tanja Dudenbostel, Steven R. Bailey, Christopher G. Kevil, Luca Cucullo, Diana Cruz-Topete
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
stress
glucocorticoids
sexual dimorphism
myocardial infarction
oxidative stress
ferroptosis
Online Access:https://www.mdpi.com/1422-0067/24/13/10994

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https://www.mdpi.com/1422-0067/24/13/10994

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