S100A8 inhibits PDGF-induced proliferation of airway smooth muscle cells dependent on the receptor for advanced glycation end-products

S100A8 inhibits PDGF-induced proliferation of airway smooth muscle cells dependent on the receptor for advanced glycation end-products

Abstract Background Airway remodeling is a key feature of asthma, characterized by increased proliferation of airway smooth muscle cells (ASMCs). S100A8 is a calcium-binding protein with a potential to regulate cell proliferation. Here, the effect of exogenous S100A8 protein on the proliferation of...

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Bibliographic Details
Main Authors: Yu-Dong Xu, Yu Wang, Lei-Miao Yin, Ling-Ling Peng, Gyoung-Hee Park, Yong-Qing Yang
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Biological Research
Subjects:
S100A8
Airway smooth muscle cells
Cell proliferation
The receptor for advanced glycation end-products
Platelet-derived growth factor
Online Access:http://link.springer.com/article/10.1186/s40659-017-0128-5

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http://link.springer.com/article/10.1186/s40659-017-0128-5

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