Cerebral microvascular endothelial cell-derived extracellular vesicles regulate blood − brain barrier function

Cerebral microvascular endothelial cell-derived extracellular vesicles regulate blood − brain barrier function

Abstract Autoreactive T lymphocytes crossing the blood-brain barrier (BBB) into the central nervous system (CNS) play a crucial role in the initiation of demyelination and neurodegeneration in multiple sclerosis (MS). Recently, extracellular vesicles (EV) secreted by BBB endothelial cells (BBB-EC) h...

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Bibliographic Details
Main Authors: Baharak Hosseinkhani, Gayel Duran, Cindy Hoeks, Doryssa Hermans, Melissa Schepers, Paulien Baeten, Joren Poelmans, Britt Coenen, Kübra Bekar, Isabel Pintelon, Jean-Pierre Timmermans, Tim Vanmierlo, Luc Michiels, Niels Hellings, Bieke Broux
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Fluids and Barriers of the CNS
Subjects:
Multiple sclerosis
BBB
EV
Online Access:https://doi.org/10.1186/s12987-023-00504-6

Internet

https://doi.org/10.1186/s12987-023-00504-6

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