Optimization of Chemically Defined Cell Culture Media for Recombinant ONTAK Immunotoxin Production

Background and Aim: Immunotoxin is a cytotoxic protein and have been proposed as a novel compound for cancer therapy. ONTAK is a recombinant immunotoxin composed diphtheria toxin fused to interleukin 2(IL2). In this study, optimization of defined culture medium for the expression of recombinant ONTA...

Full description

Bibliographic Details
Main Authors: Mohammad Heydari, Syed morteza Robatjazi, Mehadi Zeinoddini, Ehsan Darabi
Format: Article
Language:English
Published: Farname 2014-10-01
Series:Iranian Journal of Medical Microbiology
Subjects:
Online Access:http://www.ijmm.ir/browse.php?a_code=A-10-275-1&slc_lang=en&sid=1