Optimization of Chemically Defined Cell Culture Media for Recombinant ONTAK Immunotoxin Production
Background and Aim: Immunotoxin is a cytotoxic protein and have been proposed as a novel compound for cancer therapy. ONTAK is a recombinant immunotoxin composed diphtheria toxin fused to interleukin 2(IL2). In this study, optimization of defined culture medium for the expression of recombinant ONTA...
Main Authors: | Mohammad Heydari, Syed morteza Robatjazi, Mehadi Zeinoddini, Ehsan Darabi |
---|---|
Format: | Article |
Language: | English |
Published: |
Farname
2014-10-01
|
Series: | Iranian Journal of Medical Microbiology |
Subjects: | |
Online Access: | http://www.ijmm.ir/browse.php?a_code=A-10-275-1&slc_lang=en&sid=1 |
Similar Items
-
Cloning and Expression of Ontak Immunotoxin Using Intein Tag
by: SA Moosavizadeh, et al.
Published: (2016-06-01) -
Bispecific human IL2‐CCR4 immunotoxin targets human cutaneous T‐cell lymphoma
by: Haoyu Wang, et al.
Published: (2020-05-01) -
Production of Recombinant Denileukin Diftitox: Assessment in the Lab-scale Bioreactor
by: Seyed Morteza Robatjazi, et al.
Published: (2019-08-01) -
Suspended sediment transport diversity in river catchments following the 2014 phreatic eruption at Ontake Volcano, Japan
by: Kyoko S. Kataoka, et al.
Published: (2019-02-01) -
Mesothelin-Targeted Recombinant Immunotoxins for Solid Tumors
by: Brendan L. Hagerty, et al.
Published: (2020-06-01)