Widely Used Commercial ELISA Does Not Detect Precursor of Haptoglobin2, but Recognizes Properdin as a Potential Second Member of the Zonulin Family

Widely Used Commercial ELISA Does Not Detect Precursor of Haptoglobin2, but Recognizes Properdin as a Potential Second Member of the Zonulin Family

BackgroundThere is increasing evidence for the role of impaired intestinal permeability in obesity and associated metabolic diseases. Zonulin is an established serum marker for intestinal permeability and identical to pre-haptoglobin2. Here, we aimed to investigate the relationship between circulati...

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Bibliographic Details
Main Authors: Lucas Scheffler, Alyce Crane, Henrike Heyne, Anke Tönjes, Dorit Schleinitz, Christian H. Ihling, Michael Stumvoll, Rachel Freire, Maria Fiorentino, Alessio Fasano, Peter Kovacs, John T. Heiker
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Endocrinology
Subjects:
diabetes
lipid metabolism
precursor of haptoglobin2
ELISA
intestinal permeability
properdin
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2018.00022/full

Internet

http://journal.frontiersin.org/article/10.3389/fendo.2018.00022/full

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