Prioritization of schizophrenia risk genes from GWAS results by integrating multi-omics data

Abstract Schizophrenia (SCZ) is a polygenic disease with a heritability approaching 80%. Over 100 SCZ-related loci have so far been identified by genome-wide association studies (GWAS). However, the risk genes associated with these loci often remain unknown. We present a new risk gene predictor, rGA...

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Bibliographic Details
Main Authors: Dan He, Cong Fan, Mengling Qi, Yuedong Yang, David N. Cooper, Huiying Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01294-x