Facile Entry to Pharmaceutically Important 3-Difluoromethyl-quinoxalin-2-ones Enabled by Visible-Light-Driven Difluoromethylation of Quinoxalin-2-ones

Facile Entry to Pharmaceutically Important 3-Difluoromethyl-quinoxalin-2-ones Enabled by Visible-Light-Driven Difluoromethylation of Quinoxalin-2-ones

CF<sub>2</sub>H moiety has a significant potential utility in drug design and discovery, and the incorporation of CF<sub>2</sub>H into biologically active molecules represents an important and efficient strategy for seeking lead compounds and drug candidates. On the other han...

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Bibliographic Details
Main Authors: Kai-Zhong Fu, Xu-Xin Chen, Ya-Shi Zhao, Yuan-Qing Gu, Guo-Kai Liu
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceuticals
Subjects:
3-CF<sub>2</sub>H-quinoxaline-2-ones
difluoromethylation
<i>S</i>-(difluoromethyl)sulfonium salt
fluorine-containing pharmaceuticals
Online Access:https://www.mdpi.com/1424-8247/15/12/1552

Internet

https://www.mdpi.com/1424-8247/15/12/1552

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