Structural Arrangement Produced by Concanavalin A Binding to Homomeric GluK2 Receptors

Kainate receptors are members of the ionotropic glutamate receptor family. They form cation-specific transmembrane channels upon binding glutamate that desensitize in the continued presence of agonists. Concanavalin A (Con-A), a lectin, stabilizes the active open-channel state of the kainate recepto...

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Bibliographic Details
Main Authors: Cuauhtemoc U. Gonzalez, Elisa Carrillo, Vladimir Berka, Vasanthi Jayaraman
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/11/8/613