GSDMD is associated with survival in human breast cancer but does not impact anti-tumor immunity in a mouse breast cancer model

GSDMD is associated with survival in human breast cancer but does not impact anti-tumor immunity in a mouse breast cancer model

Inflammation plays a pivotal role in cancer development, with chronic inflammation promoting tumor progression and treatment resistance, whereas acute inflammatory responses contribute to protective anti-tumor immunity. Gasdermin D (GSDMD) mediates the release of pro-inflammatory cytokines such as I...

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Bibliographic Details
Main Authors: Bart Boersma, Viola Puddinu, Arnaud Huard, Sébastien Fauteux-Daniel, Pratyaksha Wirapati, Sofia Guedri, Jean-Christophe Tille, Thomas McKee, Mikael Pittet, Gaby Palmer, Carole Bourquin
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-08-01
Series:Frontiers in Immunology
Subjects:
cancer immunology
gasdermin D
breast cancer
Toll-like receptor 7
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1396777/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1396777/full

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