Bioinspired porous microspheres for sustained hypoxic exosomes release and vascularized bone regeneration

Bioinspired porous microspheres for sustained hypoxic exosomes release and vascularized bone regeneration

Exosomes derived from mesenchymal stem cells (MSCs) have demonstrated regenerative potential for cell-free bone tissue engineering, nevertheless, certain challenges, including the confined therapeutic potency of exosomes and ineffective delivery method, are still persisted. Here, we confirmed that h...

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Bibliographic Details
Main Authors: Yike Gao, Zuoying Yuan, Xiaojing Yuan, Zhuo Wan, Yingjie Yu, Qi Zhan, Yuming Zhao, Jianmin Han, Jianyong Huang, Chunyang Xiong, Qing Cai
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-08-01
Series:Bioactive Materials
Subjects:
Hypoxic exosomes
Stem cells from human exfoliated deciduous teeth
Porous microsphere
Sustained release
Vascularized bone regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X22000561

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http://www.sciencedirect.com/science/article/pii/S2452199X22000561

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