NEU1 Regulates Mitochondrial Energy Metabolism and Oxidative Stress Post-myocardial Infarction in Mice via the SIRT1/PGC-1 Alpha Axis

NEU1 Regulates Mitochondrial Energy Metabolism and Oxidative Stress Post-myocardial Infarction in Mice via the SIRT1/PGC-1 Alpha Axis

ObjectiveNeuraminidase 1 (NEU1) participates in the response to multiple receptor signals and regulates various cellular metabolic behaviors. Importantly, it is closely related to the occurrence and progression of cardiovascular diseases. Because ischemic heart disease is often accompanied by impair...

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Bibliographic Details
Main Authors: Zhen Guo, Di Fan, Fang-Yuan Liu, Shu-Qing Ma, Peng An, Dan Yang, Min-Yu Wang, Zheng Yang, Qi-Zhu Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
neuraminidase 1
myocardial infarction
mitochondrial metabolism
SIRT1
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.821317/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.821317/full

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